Verena M. Dirsch
Univ.-Prof. Dr.
Vice-Head of
Pharmaceutical Sciences
University Professor
room 2G 452 (floor 4)
+43-1-4277-55270
- Molecular Targets Group
- Biomolecules for a Healthy Lifespan (PIs: Verena Dirsch and Karl-Heinz Wagner)
- 2022 - 2025
FWF – Project P35241
The Neolignan-derived Rexinoid LRK071 - 2016 - 2019
BMWFW: SINO AUSTRIA III
China: TCM-Research Cluster Austria III: Identification of natural products from Paridis rhizoma (Chonglou) as liver X receptor (LXR) and farnesoid X receptor (FXR) ligands.
https://oravm13.noc-science.at/apex/f?p=115:3:::NO::P3_PROJIDF,P3_PREVIOUS_PAGE:30706,5 - 2016 - 2017
Austria Wirtschaftsservice: PRIZE
Joint project between Universitiy of Vienna and Technical Universitiy Vienna
Synthetische Lignane als Proliferationshemmer bei Cardiovasculären Erkrankungen. - 2015 - 2018
Member of the research platform "Metabolomics School University of Vienna" (University of Vienna; Head: Wolfram Weckwerth)
Joint project between the Faculty of Life Sciences, Faculty of Chemistry, and the Faculty of Geoscience - 05/2016 - 04/2017
Austria Wirtschaftsservice GmbH (AWS)
Herstellungsverfahren für Leoligin-artige Lignane und deren Effekt auf das Wachstum von glatten Gefäßmuskelzellen - 2013 - 2015
FFG Bridge Project 841283
Establishing new models for the metabolic syndrome as screening platform for herbal drugs - 2012 - 2014
EU Contract No. PIIF-GA-2009-252881
TCM-VASC: Chinese Medicines used against Cardiovascular Disease.
http://cordis.europa.eu/project/rcn/106082_en.html - 2011 - 2017
Member of the Research platform “Active Aging” (University of Vienna; Head: Karl-Heinz Wagner)
Joint project between the Faculty of Life Sciences and the Center of Sport Sciences
http://www.univie.ac.at/antiox/projects_show.php?pr_id=15 - 2011 - 2014
FWF-NFN-Project S10704-B13 (Project Part PP04)
Drugs from nature targeting inflammatory.
www.uibk.ac.at/pharmazie/pharmakognosie/dnti - 2011 - 2014
FWF – Project P23317 (Co-PI; PI: Elke Heiss)
Antiproliferative and antimigratory activity of I3MO.
http://www.univie.ac.at/pharmakognosie/I3MO - 2011 - 2014
Project within the Graduate Program “Bioactivity Profiling & Metabolism” (University of Vienna)
Natural Products and their Impact on miRNAs in Activated Vascular Smooth Muscle Cells
http://biopromotion.univie.ac.at/projects/subproject-1/ - 2009 - 2012
EU Coordination action; no 223154
GP-TCM: Good Practice in Traditional Chinese Medicine Research in the Post-genomic Era
http://www.gp-tcm.org/ - 2008 - 2011
FWF-NFN-Project S10704-B03
Drugs from nature targeting inflammatory.
www.uibk.ac.at/pharmazie/pharmakognosie/dnti - 2007 - 2010
Project within the Graduate Program "Molecular Drug Targets" (University of Vienna)
Virtual and Real screening of Natural Products to Find Effective Modulators of Protein Tyrosine Phosphatase
http://www.mdpi.com/2218-0532/77/6/199 - 2006 - 2010
FWF-Project P18982-B17 Resveratrol and Shp2
http://pf.fwf.ac.at/de/wissenschaft-konkret/project-finder/4234 - 2006 - 2009
EU Contract No. LSHB-CT-2004-503467
Pro Kinase Research: Protein kinases and phosphatases as targets for new anti-atherogenic compounds.
www.proteinkinase-research.org/ - 2003 - 2006
DFG Sachbeihilfe VO 376/10-1/2 (Co-PI, PI: Angelika M. Vollmar, University of Munich)
Signaltransduction of apoptosis-induction by cephalostatin-1, isolated from a marine organism
www.cup.uni-muenchen.de/pb/aks/vollmar/ - 2001 - 2002
DPhG Foundation for Young Scientists T 197/01.003.00
Sesqiterpene lactones and apoptosis - 1994 - 1995
DFG-Fellowship DI 599/1-1
Postdoc at the Columbia University in New York
- 1984-1989
Studies of Pharmacy, University of Munich (LMU) - 1990
Approbation (approval as apothecary) - 1993
Graduation (Dr. rer.nat. summa cum laude ) University of Munich
(group of Prof. H Wagner; research field: phytochemistry) - 1994-1995
Postdoctoral fellow of the German Research Council (DFG) at the Department of Chemistry, Columbia University, New York, USA
(group of Prof. K Nakanishi; research field: natural product chemistry) - 1995-1998
Research associate at the Institute of Pharmacology, Toxicology and Pharmacy, of the Veterinarian School, University of Munich
(group of Prof. AM Vollmar; research field: pharmacology) - 1998-2004
Scientific assistant and from 2003 Lecturer (Privatdozentin) at the Department of Pharmacy, University of Munich
(group of Prof. AM Vollmar; research field: natural product pharmacology) - 2002/2003
State doctorate (Habilitation) and venia legendi for Pharmaceutical Biology as well as Pharmacology - 10/2004
Professor of Pharmacognosy at the Department of Pharmacognosy, University of Vienna - since 2005
Speaker of the Faculty Key Research Area „Drug Discovery from Nature” (2005-2021), from 2022: „Biomolecules for a Healthy Lifespan” (Faculty of Life Sciences, University of Vienna) - Since 2006
Head of the Department (since 03/2021: Division) of Pharmacognosy, University of Vienna - 2008-2014
Vice-Dean of the Faculty of Life Sciences, University of Vienna - 2009-2019
Deputy-member of the Senate, University of Vienna - 2014-2019
Deputy Speaker of the Center of Pharmaceutical Sciences, University of Vienna - 2020
Speaker of the Center of Pharmaceutical Sciences, University of Vienna - Since 03/2021
Vice-Head of the new Department of Pharmaceutical Sciences
- 1994
Postdoctoral Fellowship granted by the DFG (German Research Council) - 1997
Präventionspreis der Deutschen Herzhilfe 1997 - 1998
PHOENIX Pharmazie-Wissenschaftspreis (Pharmacology) - 2011
PHOENIX Pharmazie-Wissenschaftspreis (Pharmaceutical Biology) - 2011
KIWIE-Silver medal 2011– from the KWIA (Korean International Woman’s Invention Association)
ORCID iD: 0000-0002-9261-5293
Publications
Dirsch V. 3. Quallen - Gefährliche Schönheiten, Thomas Heeger, Wissenschaftliche Verlagsgesellschaft mbH Stuttgart, 1998. Toxicon. 2000;38:1879-1879.
Dirsch V, Stuppner H, Ellmerer-Müller EP, Vollmar AM. Structural requirements of sesquiterpene lactones to inhibit LPS-induced nitric oxide synthesis in RAW 264.7 macrophages. Bioorganic & Medicinal Chemistry. 2000;8(12):2747-2753.
Dirsch V. 1. Afrikanische Arzneipflanzen und Jagdgifte: Chemie, Pharmakologie, Toxikologie, Hans Dieter Neuwinger: 2nd edition, Wissenschaftliche Verlagsgesellschaft mbH Stuttgart. Toxicon. 1999;37:1087-1088.
Zidorn C, Dirsch V, Della Loggia R, Vollmar AM, Stuppner H. Antiinflammatory activities of hypocretenolides from Leontodon hispidus. Planta Medica: natural products and medicinal plant research. 1999;65:704-708.
Dirsch V, Gerbes A, Vollmar AM. Ajoene, a compound of garlic, induces apoptosis in human promyeloleukemic cells, accompanied by generation of reactive oxygen species and activation of nuclear factor kappaB. Molecular Pharmacology. 1998;53:402-407.
Dirsch V, Kiemer A, Wagner H, Vollmar AM. Effect of allicin and ajoene, two compounds of garlic, on inducible nitric oxide synthase. Atherosclerosis. 1998;139:333-339.
Dirsch V, Wolf E, Wanke R, Schulz R, Hermanns W, Vollmar AM. Effect of chronic GH overproduction on cardiac ANP expression and circulating ANP levels. Molecular and Cellular Endocrinology. 1998;144:109-118.
Dirsch V, Stuppner H, Vollmar AM. The Griess assay: suitable for a bio-guided fractionation of anti-inflammatory plant extracts? Planta Medica: natural products and medicinal plant research. 1998;64:423-426.
Dirsch V, Kiemer A, Wagner H, Vollmar AM. The triterpenoid quinonemethide pristimerin inhibits induction of inducible nitric oxide synthase in murine macrophages. European Journal of Pharmacology. 1997;336:211-217.
Kawamura A, Berova N, Dirsch V, Mangoni A, Nakanishi K, Schwartz G et al. Picomole scale stereochemical analysis of sphingosines and dihydrosphingosines. Bioorganic & Medicinal Chemistry. 1996 Jul;4(7):1035-43. doi: 10.1016/0968-0896(96)00092-2
Dirsch V, Frederico J, Zhao N, Cai G, Chen Y, Vunnam S et al. A two-step chemical and circular dichroic method for assigning the absolute configurations of sphingosines. Tetrahedron Letters. 1995;36:4959–4962. doi: 10.1016/0040-4039(95)00998-R
Dirsch V, Lacaille-Dubois MA, Wagner H. Dracoside, a New Steroidal Saponin from Helleborus purpurascens. Natural Product Research. 1994;4:29-33. doi: 10.1080/10575639408043888
Dirsch V, Neszmélyi A, Wagner H. A trimeric propelargonidine from the stem bark of Heisteria pallida Engl. Phytochemistry. 1993;34:291-293.
Dirsch V, Wiemann W, Wagner H. Antiinflammatory activity of triterpene quinone-methides and proanthocyanidines from the stem bark of Heisteria pallida. Pharmaceutical and Pharmacological Letters. 1992;2:184-186.